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GALLERY: Human Polyomavirus Infection

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Polyomaviruses are unenveloped double-stranded DNA viruses with circular genomes of around 5000 base pairs . The genome is packaged in a viral capsid of about 40-50 nanometers in diameter, which is icosahedral in shape (T=7 symmetry). [2] [11] The capsid is composed of 72 pentameric capsomeres of a protein called VP1 , which is capable of self-assembly into a closed icosahedron; [12] each pentamer of VP1 is associated with one molecule of one of the other two capsid proteins, VP2 or VP3 . [4]

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